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Studies were included if subjects had a noncontributory medical history; underwent nonsurgical root canal treatment during the study; there was comparison between single- and multiple-visit root canal treatment; and if outcome was measured in terms of pain degree or prevalence of flare-up.
Data were extracted using a standard data extraction sheet. Because of variations in recorded outcomes and methodological and clinical heterogeneity, a meta-analysis was not carried out, although a qualitative synthesis was presented.
Sixteen studies fitted the inclusion criteria in the review, with sample size varying from 60–1012 cases. The prevalence of postoperative pain ranged from 3–58%. The heterogeneity of the included studies was far too great to yield meaningful results from a meta-analysis.
Compelling evidence is lacking to indicate any significantly different prevalence of postoperative pain or flare-up following either single- or multiple-visit root canal treatment.
(Source: Evidence-Based Dentistry (2009) 10, 16. doi:10.1038/sj.ebd.6400630)
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